Gabapentin for Dogs: A Growing Trend in Veterinary Medicine
Gabapentin has a wide range of uses in veterinary medicine, and prescribing gabapentin for dogs is becoming more common among veterinarians.
Here’s everything you need to know about gabapentin for dogs.
Key Points to Remember

gabapentin for dogs
- Veterinarians commonly prescribe gabapentin to treat pain, seizures, and anxiety in dogs.
- Gabapentin is a human medication, and its use in veterinary medicine is considered “off-label,” meaning it is not FDA-approved for pets.
- Sedation is the main potential side effect of gabapentin, and the level of sleepiness can vary from one dog to another.
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What Is Gabapentin for Dogs?
Gabapentin for dogs is a medication commonly used by veterinarians to manage pain, treat seizures, and alleviate anxiety. It is classified as an anticonvulsant and analgesic.
Although the exact mechanism of how gabapentin works is not fully understood, it is believed to prevent the stimulation of nerve cells, helping to reduce pain and control seizures.
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What Is Gabapentin Used for in Dogs?
Gabapentin for dogs is a human medication, and its use in veterinary care is considered “off-label,” meaning it is not officially FDA-approved for pets. Despite this, veterinarians may prescribe gabapentin to help manage pain, seizures, and anxiety in dogs.
Preventing Seizures
Gabapentin has anticonvulsant effects, making it useful as an adjunctive treatment for dogs with refractory seizures or for those whose current medication regimen is no longer effective.
Controlling Pain
Gabapentin for dogs acts as an analgesic, offering relief from chronic and neuropathic pain. It is frequently used to treat the chronic pain associated with conditions like degenerative joint disease and arthritis. It can also be beneficial when combined with other pain relievers, such as nonsteroidal anti-inflammatory drugs (NSAIDs) or opioids, to manage post-surgical pain.
Easing Anxiety
Gabapentin can be helpful in managing general anxiety in dogs, particularly for stress caused by thunderstorms or vet visits. It is believed to reduce the release of excitatory neurotransmitters in the brain, which helps to alleviate anxiety and provide a more relaxed state for the dog. If your dog struggles with anxiety during thunderstorms, vet visits, or other stress-inducing situations, you may also consider using a Thundershirt® in conjunction with gabapentin for dogs. Your vet can guide you in determining if this medication is suitable for your dog’s anxiety.
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**What Are the Side Effects of Gabapentin for Dogs?**
The primary side effect of gabapentin for dogs is sedation, and the degree of drowsiness can vary depending on the individual dog. If the dog becomes excessively sedated, the veterinarian may adjust the dosage to find the most effective and comfortable amount.
Like all medications, there is a small chance that a dog could be allergic to gabapentin, in which case it should not be used. Additionally, gabapentin should be used cautiously in dogs with kidney or liver disease, as it may take longer for the body to metabolize the drug.
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**What’s the Gabapentin Dosage for Dogs?**
The dosage of gabapentin for dogs can vary significantly depending on the condition being treated.
Gabapentin is available in several human-labeled forms, including:
– 100 mg capsules
– 300 mg capsules
– 400 mg capsules
There is also an oral solution available at 250 mg/5 mL. However, some solutions may contain xylitol, which is highly toxic to dogs. Your veterinarian will ensure that the form of gabapentin you use is safe for your pet.
For very small dogs, the human formulations may not be suitable. In such cases, a compounding pharmacy can prepare a customized dose or form based on your veterinarian’s prescription.
Gabapentin is generally administered orally two to four times per day, with or without food. Always follow the instructions provided on the medication label or consult your vet if you’re unsure about the proper dosage for your dog.
Gabapentin typically begins working within one to two hours of administration, providing short-term relief. Its effects last for about 24 hours, but in dogs with kidney or liver issues, it may remain in their system longer.
If gabapentin is prescribed for seizure control, it should never be stopped abruptly, as doing so could trigger withdrawal seizures. Always consult your veterinarian before discontinuing any medication.
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**Is It Safe to Combine Gabapentin and Trazodone for Dogs?**
Trazodone is a widely prescribed medication to help manage anxiety in dogs, particularly to ease stress before veterinary appointments or during recovery after surgery. Gabapentin, frequently used to alleviate both anxiety and pain, is commonly prescribed alongside trazodone in these situations. These two medications can be safely used together to provide more effective relief for your dog’s anxiety and discomfort.
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**Can Dogs Take CBD and Gabapentin?**
If your dog is taking gabapentin for conditions such as pain or anxiety, you may be considering adding CBD oil. However, using CBD and gabapentin together is not recommended due to the increased risk of sedation.
Before introducing any additional medications or supplements to your dog’s routine, always consult with your veterinarian to ensure their safety and compatibility with existing treatments.
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**Which is More Effective for Pain in Dogs: Tramadol or Gabapentin?*
Tramadol, once a commonly used pain reliever for dogs, is becoming less popular among veterinarians. Research has shown that tramadol may not be as effective as previously believed, particularly for managing pain related to osteoarthritis in dogs. While studies continue on this topic, gabapentin for dogs is increasingly being used as a pain management alternative.
In some cases, veterinarians may choose to combine gabapentin with other pain medications, including tramadol, to provide more comprehensive pain relief for dogs. Your vet will determine the most appropriate treatment plan based on your dog’s needs.